Low Dose Naltrexone (LDN) is a powerful anti-inflammatory, immune modulating drug therapy that can be a “game changer” for people with physical or neurological chronic inflammation. However, it can be a bit “high maintenance” and expensive for patients to find the right dose. Traditionally, you would go to a doctor ($$) and get a prescription for LDN, get it filled at a compounding pharmacy ($$) that weighs out a custom capsule or tablet in your exact prescribed dose, take that initial dose a few weeks or months, then go back for another doctors visit ($$) to get the dose adjusted, then back to the compounding pharmacy for a newly dosed formula ($$), etc, etc.
If you are comfortable compounding & titrating the drug yourself, making your own LDN out of 50mg naltrexone tablets is really simple. And affordable! Here’s how:
Materials needed:
- 2 x naltrexone 50mg tablets (generic)
- 500mL bottle of sealed bottled water
- 30mL graduated shot glass
Directions:
- Drop two 50mg naltrexone tablets into a 500mL bottle of water.
- Let tablets dissolve for 30 minutes and then shake vigorously.
- When fully and completely dissolved (some tiny white sediments of tablet binder will remain), shake bottle & pour the desired dose into a shot glass and consume.
- Store the bottle in the refrigerator for cleanest & best results.
Milliliters of Liquid | Approximate Dose of LDN |
5 mL | 1 mg |
10 mL | 2 mg |
15 mL | 3 mg |
20 mL | 4 mg |
25 mL | 5mg |
The inventor of LDN therapy, Dr. Bernard Bihari, has been quoted as saying LDN must be taken at bedtime for it to work and cause proper endorphin release.
I and others have found it works fine if taken at any time of the day or night. I pour out my dose before bedtime and take my LDN “shot” upon awakening.
Great info thank you!